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Parenteral Products

B.Pharmacy, 5th Semester, 2024 (2023-2024) - Assignments

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Parenteral Products B.Pharmacy 5th Semester 2024 (2023-2024) Previous Year's Question Papers/Notes Download - HK Technical PGIMS



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Parenteral Products

Parenteral Products

Definition

Types of Parenteral Products

  1. Based on volume
    • Small Volume Parenteral (SVP)
    • large Volume Parenteral (LVP)

       2. Based on states of products

    • Solutions
    • Suspensions
    • Emulsions
    • Lipophilized Powders (Freeze dried Powder)
    • Implants
    • Infusions

       3. Based on type of packaging

    • Single Dose
    • Multiple Dose

Pre formulation Factors Affecting Parenteral Preparation

  • Solubility/pKa/pH
  • Solid State Characteristics
  • Chemical Modification of the drug
  • Polymorphism

Advantages of parenteral products

Disadvantages of parenteral products

Essential requirements for formulation

  1. Vehicles
    • Aqueous vehicles
    • Non aqueous vehicles
  2. Additives
    • Solubilizing agents
    • Stabilizers
    • Buffering agents
    • Antibacterial agents
    • Chelating agents
    • Suspending agents, Emulsifying agents, Wetting agents

Tonicity in Parenetral Preparation

  • Hypertonic
  • Isotonic
  • Hypotonic

Importance of Isotonicity

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