Unit 2 Liquid Orals B.Pharmacy 5th Semester 2020 (2019-2020) Previous Year's Question Papers/Notes Download - HK Technical PGIMS

Liquid Orals

Definition

Type

Solution

Advantages

Disadvantages

Formulation of Solution

• Drug Solubility
• Vehicle or Solvent
  • Types
• Preservative
• Colourant
• Flavours
• Sweetners
• Viscousity Modifiers
• Buffering Agents
• Anti-oxidant

Manufacturing Considerations

• Facilities
• Raw Materials
• Equipments
• Compounding
• Filteration
• Filling
  • Gravimetric Filling
  • Volumetric Filling
  • Constant Line Filling

Suspension

Ideal Properties

Classification

Formulation of Suspension

• Wetting Agent
• Floculating Agent
• Thickener
• Preservatives
• Colouring Agents
• Sweetners and Flavouring Agent

Emulsion

Classification

Ingredients Used in the Formulation of Emulsion

• Emulsifying Agent
• Preservative
• Anti-Oxidant
• Sweetening Agnet, Colouring Agnet, Flavouring Agent

Formulation of Emulsion

• Selection of Oil Phase
• Selection Aqueous Phase
• Selection of Emulsifying Agent

Site of Application

Manufacturing of Emulsion

• Dry Gum Method
• Wet Gum Method
• Bottle Method

Evaluation of Liqiud Orals

• Visual Inspection
• Taste and Odour
• pH Measurement
• Stability Studies
• Viscousity Measurements
• Sucrose Concentration
• Alcohol Content
• Microbiological Test
• Phase Separation 
• Degree of Floculation
• Uniformity of Mass
• Uniformity of Volume
• Assay