HK Technical Logo
Unit 4: Complexation and Protein Binding 3rd Semester B.Pharmacy Lecture Notes,BP302T Physical Pharmaceutics I,Handwritten Notes,B.pharmacy 3rd semester,2024 (2023-2024),BP302T Physical Pharmaceutics I,Complexion and protein binding,

Unit 4: Complexation and Protein Binding

B.Pharmacy, 3rd Semester, 2024 (2023-2024) - Lecture Notes

  • Download
58 4 Report Jun 25, 2024

Unit 4: Complexation and Protein Binding B.Pharmacy 3rd Semester 2024 (2023-2024) Previous Year's Question Papers/Notes Download - HK Technical PGIMS



More Related Content


Unit 4: Complexation and Protein Binding

Complexation and Protein Binding

Introduction: Complexation, Ligand, Metal Atom

Classification of Complexation

  1. Coordinate/ Metal Complexes
    • Inorganic
    • Chelate
    • Olefin
    • Aromatic

     2. Organic Molecular Complexes

    • Quinhydrone Type
    • Caffeine Complex
    • Picric Acid Type
    • Polymeric Complex

    3. Inclusion/ Occlusion Complexes

    • Clathrate Complex
    • Channel Lattice
    • Layer Type
    • Monomolecular and Macromolecular

Application of Complexation in Pharmacy

  1. In various types of poisonings
  2. In drug absorption and bioavailability from various dosage forms
  3. In Solubilization
  4. In Diagnosis
  5. To alter physiochemical and biopharmaceutical properties of a drug
  6. Assay of drug
  7. Preservation

Method of Analysis

  1. Methods
  1. Method of Continous Variation
  2. Distribution Method
  3. Solubility Method
  4. pH Titration Method

Protein Binding

Significance of Protein Binding

  • Absorption
  • Distribution
  • Elimination

Factors Affecting Protein Binding

  • Physiochemical Properties of Drug
  • Affinity of Drug for Binding Compound
  • Concentration of Drug

Complexation and Drug Action

Crystalline Structure of Complexes

Thermodynamically Treatment of Stability Constant

 

Did you find, what you are looking for?
Yes
No

Find what you need faster with our free app!


In case, Feaures are not working on this website, please update your browser or use another browser. View Supported Browser List. Further if you think this is an error, please feel free to contact us at [email protected] or you may also Chat with us.


Copyright © 2024 HK Technical