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30 4 Report Jun 22, 2024

PHARMACEUTICAL AEROSOLS B.Pharmacy 3rd Year 2022 (2021-2022) Previous Year's Question Papers/Notes Download - HK Technical PGIMS



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PHARMACEUTICAL AEROSOLS

PHARMACEUTICAL AEROSOLS

Introduction: Definition, Advantages, Disadvantages

Types of Aerosols

Types of Aerosol Systems

Componenets of Aerosols

  1. Propellants: Definition, Ideal Properties, Classifiaction
  • Liquified Gas: CFC, Hydrocarbons, Advantages, Disadvantages
  • Compressed Gas: Functioning, Uses

    B. Container: Classification, Advantages, Disadvantages, Uses

  • Metal: Tinplated Steel, Aluminium, Stainless Steel
  • Glass
  • Plastics

    C. Valve: Purpose, Types

  • Components or parts of valve: Ferrule or Mounting Cap, Housing or Valve Body, Stem, Gasket, Spring, Dip tube

    D.Actuator : Functions, Types

  • Spray Actuator
  • Foam Actuator
  • Solid Stream Actuator
  • Special Actuator

    E. Product

Manufacturing Methods of Aerosols

  • Pressure Filling Apparatus: Procedure, Advantages, Disadvantages
  • Cold Filling Apparatus: Construction,  Procedure, Advantages, Disadvantages
  • Compressed Gas Filling Apparatus: Construction,  Procedure

Quality Control or Evaluation Test for Aerosols

  • Fammability and Combustability
  1. Flash Point
  2. Flame Extension
  • Physiochemical Characters
  1. Vapour Pressure
  2. Density
  3. Moisture Content
  4. Identification of Propellants
  5. pdt: propellant ratio
  • Performance
  1. Aerosole Valve Discharge Rate
  2. Spray Pattern
  3. Dosage with Metered Valve
  4. Net Content
  5. Foam Stability
  6. Particle Size Determination
  7. Leakage
  • Biological Characters
  1. Therapeutic Activity
  2. Toxicity

Applications of Pharmaceutical Aerosols

  • Local Analgesis
  • Anti-inflammatory Agents
  • Antiseptic and Skin Sterilizers
  • Skin Dressings
  • Antibiotics
  • Antifungal Agents
  • Preparation for Administration to Body Cavities

 

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