Nanotechnology Unit 3-5 B.Pharmacy 8th Semester 2025 (2024-2025) Previous Year's Question Papers/Notes Download - HK Technical PGIMS

Biomedical Applications of Nanotechnology 

A) Nanotechnology Productss Used for Invitro Diagnostics

Introduction

Nanomaterials for Medical Diagnosis

Nanodevices or Nanoproducts Used in Diagnostics

1. Centilevers

2. Nanopores
3. nanotubes
4. Quantum Dots (QD)
5. Nanoshells
6. Dendrimers
7. Magnetic Nanoparticles (MNP)

Application in Targetting

• Cancer
• Infectious Disease
• Autoimmune Diseases
• Cardiovascular Disease
• Ocular Disease
• Pulmonary Disease

Application in Imaging

Medical Imaging

• MRI: Gadolinium, Carbon, Manganese Silicon
• CT: Gold Nanoparticles, Iodine, Bismuth
• PET: Gold Nanoparticles, Copper
• Single Photon Emission Computerised Tomography: Gold Nanoparticles, Technetium
• Optical Imaging: Fluorescence, Quantum Dots, Gold Nanoparticles
• Ultrasound
• Photoacoustic Imaging: Gold Nanoparticles, Carbon-Nanotube (CNT), Fluoresecnt

Characterisation of Nanoparticles

1. Size and Surface Morphology
2. Specific Surafce Area
3. Surface Charge and Electrophoretic Mobility
4. Density
5. Molecular Weight Measurement of Nanoparticles
6. Drug Entrapment Efficacy
7. Kinetic Study 
8. Chemical Charaterisation (Lipososmes)
9. Bilogical Characterisation (Lipososmes)
10. Invitro Release Studies
11. Stability Studies of Nanoparticles