The science behind liquid dosage forms, a critical delivery system for drugs with poor solubility or patient compliance challenges. This guide covers:
Types & Advantages: Solutions, suspensions, emulsions; ideal for pediatric/geriatric patients.
Key Excipients: Vehicles (water, PEG), preservatives, surfactants, sweeteners, and viscosity modifiers.
Solubility Enhancement: Micronization, nano-suspensions, pH adjustment, co-solvency, and supercritical fluid technology.
Stability & Bioavailability: Techniques to overcome oxidation, microbial growth, and poor dissolution.
Key Highlights:
Formulation Protocols: Step-by-step excipient selection for monophasic (solutions) and biphasic (emulsions/suspensions) systems.
Clinical Applications: Masking bitter tastes, improving absorption, and enabling flexible dosing.
Innovative Techniques: Nano-suspensions for hydrophobic drugs (e.g., paclitaxel), supercritical fluid processing for particle size reduction.
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