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Essentials of Medical Pharmacology 6th Edition

BPharmacy, 4th Semester, 2020 - Notes

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-By Private account -Apr. 17, 2020

Essentials of Medical Pharmacology 6th Edition BPharmacy 4th semester 2020 Previous Year's Question Papers/Notes Download - HK Technical PGIMS

Contents Section 1 General Pharmacological Principles 1. Introduction, Routes of Drug Administration ...............................................................................3 2. Pharmacokinetics: Membrane Transport, Absorption and Distribution of Drugs ...............11 3. Pharmacokinetics: Metabolism and Excretion of Drugs, Kinetics of Elimination ................23 4. Pharmacodynamics: Mechanism of Drug Action; Receptor Pharmacology...........................37 5. Aspects of Pharmacotherapy; Clinical Pharmacology and Drug Development....................59 6. Adverse Drug Effects ......................................................................................................................78 Section 2 Drugs Acting on Autonomic Nervous System Autonomic Nervous System: General Considerations ..............................................................88 7. Cholinergic System and Drugs ......................................................................................................93 8. Anticholinergic Drugs and Drugs Acting on Autonomic Ganglia ........................................ 106 9. Adrenergic System and Drugs ................................................................................................... 116 10. Antiadrenergic Drugs (Adrenergic Receptor Antagonists) and Drugs for Glaucoma ..................................................................................................................... 132 Section 3 Autacoids and Related Drugs 11. Histamine and Antihistaminics ................................................................................................. 151 12. 5-Hydroxytryptamine, its Antagonists and Drug Therapy of Migraine .............................. 162 13. Prostaglandins, Leukotrienes (Eicosanoids) and Platelet Activating Factor........................ 173 14. Nonsteroidal Antiinflammatory Drugs and Antipyretic-Analgesics ................................... 184 15. Antirheumatoid and Antigout Drugs ........................................................................................ 202 Section 4 Respiratory System Drugs 16. Drugs for Cough and Bronchial Asthma ................................................................................... 213 Section 5 Hormones and Related Drugs Introduction ................................................................................................................................... 231 17. Anterior Pituitary Hormones ...................................................................................................... 233 18. Thyroid Hormone and Thyroid Inhibitors ............................................................................... 242 19. Insulin, Oral Hypoglycaemic Drugs and Glucagon ................................................................ 254 20. Corticosteroids ............................................................................................................................... 275 21. Androgens and Drugs for Erectile Dysfunction ...................................................................... 288 22. Estrogens, Progestins and Contraceptives ................................................................................ 297 23. Oxytocin and Other Drugs Acting on Uterus ........................................................................... 319 24. Drugs Affecting Calcium Balance ............................................................................................. 325 Section 6 Drugs Acting on Peripheral (Somatic) Nervous System 25. Skeletal Muscle Relaxants .......................................................................................................... 339 26. Local Anaesthetics ........................................................................................................................ 351 Section 7 Drugs Acting on Central Nervous System 27. General Anaesthetics ................................................................................................................... 365 28. Ethyl and Methyl Alcohols .......................................................................................................... 380 29. Sedative-Hypnotics ...................................................................................................................... 388 30. Antiepileptic Drugs ...................................................................................................................... 401 31. Antiparkinsonian Drugs .............................................................................................................. 414 32. Drugs Used in Mental Illness: Antipsychotic and Antimanic Drugs ................................... 423 33. Drugs Used in Mental Illness: Antidepressant and Antianxiety Drugs .............................. 439 34. Opioid Analgesics and Antagonists .......................................................................................... 453 35. CNS Stimulants and Cognition Enhancers ............................................................................... 469 viii Contents Section 8 Cardiovascular Drugs Cardiac Electrophysiological Considerations ........................................................................... 476 36. Drugs Affecting Renin-Angiotensin System and Plasma Kinins ......................................... 479 37. Cardiac Glycosides and Drugs for Heart Failure..................................................................... 493 38. Antiarrhythmic Drugs .................................................................................................................. 508 39. Antianginal and Other Anti-ischaemic Drugs ......................................................................... 521 40. Antihypertensive Drugs .............................................................................................................. 539 Section 9 Drugs Acting on Kidney Relevant Physiology of Urine Formation .................................................................................. 557 41. Diuretics ......................................................................................................................................... 561 42. Antidiuretics .................................................................................................................................. 574 Section 10 Drugs Affecting Blood and Blood Formation 43. Haematinics and Erythropoietin ................................................................................................ 581 44. Drugs Affecting Coagulation, Bleeding and Thrombosis ...................................................... 593 45. Hypolipidaemic Drugs and Plasma Expanders ...................................................................... 612 Section 11 Gastrointestinal Drugs 46. Drugs for Peptic Ulcer .................................................................................................................. 627 47. Drugs for Emesis, Reflux and Digestive Disorders ................................................................ 639 48. Drugs for Constipation and Diarrhoea ...................................................................................... 651 Section 12 Antimicrobial Drugs 49. Antimicrobial Drugs: General Considerations ........................................................................ 667 50. Sulfonamides, Cotrimoxazole and Quinolones ....................................................................... 682 51. Beta-Lactam Antibiotics ............................................................................................................... 694 Contents ix 52. Tetracyclines and Chloramphenicol (Broad-Spectrum Antibiotics) .................................... 710 53. Aminoglycoside Antibiotics ........................................................................................................ 719 54. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics ....................................................................................................................... 727 55. Antitubercular Drugs ................................................................................................................... 739 56. Antileprotic Drugs ........................................................................................................................ 751 57. Antifungal Drugs .......................................................................................................................... 757 58. Antiviral Drugs .............................................................................................................................. 767 59. Antimalarial Drugs ....................................................................................................................... 780 60. Antiamoebic and Other Antiprotozoal Drugs .......................................................................... 797 61. Anthelmintic Drugs ...................................................................................................................... 808 Section 13 Chemotherapy of Neoplastic Diseases 62. Anticancer Drugs .......................................................................................................................... 819 Section 14 Miscellaneous Drugs 63. Immunosuppressants, Gene Therapy ...................................................................................... 837 64. Drugs Acting on Skin and Mucous Membranes ..................................................................... 845 65. Antiseptics, Disinfectants and Ectoparasiticides ..................................................................... 857 66. Chelating Agents ........................................................................................................................... 865 67. Vitamins ......................................................................................................................................... 869 68. Vaccines and Sera ........................................................................................................................ 879 69. Drug Interactions .......................................................................................................................... 889 Selected References for Further Reading ................................................................................. 897 Appendix 1: List of Essential Medicines ..................................................................................... 903 Appendix 2: Prescribing in Pregnancy ........................................................................................ 908 Appendix 3: Drugs in Breastfeeding ............................................................................................ 911 Appendix 4: Drugs and Fixed Dose Combinations Banned in India ........................................ 915 Index ................................................................................................................................................ 917



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