Bioprocess Engineering & Technology: Fermentation, Chromatography, and Downstream Processing M.Pharmacy 1st Semester 2022 (2021-2022) Previous Year's Question Papers/Notes Download - HK Technical PGIMS

M.Pharm 1st Semester Bioprocess Engineering exam paper explores advanced topics like mass transfer, fermentation pH control, bioreactor aseptic conditions, and downstream processing techniques, crucial for biopharmaceutical and industrial biotech applications.

Key Highlights:

1. Core Bioprocess Concepts:

   • Mass Transfer: Theory, coefficient determination, and industrial relevance.

   • Fermentation Control: pH measurement, continuous vs. fed-batch cultures.

   • Sterilization: HTST (High-Temperature Short-Time) pros/cons.

2. Downstream Processing:

   • Chromatography: Ion exchange (IEC) principles and applications.

   • Cell Disruption & Filtration: Methods for product recovery.

   • Centrifugation: Industrial-scale separation techniques.

3. Advanced Applications:

   • Strain Improvement: Strategies for yield enhancement.

   • Biotransformation: Microbial conversion of steroids.

   • Vitamin C Bioprocessing: Industrial production methods.