Antipsychotic Drugs: Classification, Mechanism of Action & Structure-Activity Relationships

B.Pharmacy, 4th Year, 2024 (2023-2024) - Practical

BP402T Medicinal Chemistry I

Pandit Bhagwat Dayal Sharma University of Health Sciences

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HK Technical PGIMS

24 0 Report Feb 12, 2025

Om Ranpise

Antipsychotic Drugs: Classification, Mechanism of Action & Structure-Activity Relationships B.Pharmacy 4th Year 2024 (2023-2024) Previous Year's Question Papers/Notes Download - HK Technical PGIMS

SAR antipsychotics Haloperidol Phenothiazines Structure-activity relationships Synthesis of haloperidol Uses of antipsychotics Symptoms of psychosis Classification of antipsychotics

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Antipsychotic Drugs: Classification, Mechanism of Action & Structure-Activity Relationships

Antipsychotics: 
This document covers the following topics related to antipsychotic medications:

Classification of antipsychotics: Typical (1st generation) vs. atypical (2nd generation) antipsychotics.
Mechanism of action: How antipsychotics interact with dopamine receptors in the brain to reduce psychosis symptoms.
Specific antipsychotic drugs:
Haloperidol: A typical antipsychotic used for schizophrenia and delirium.
Phenothiazines: A class of typical antipsychotics used for severe mental and emotional disorders.

Structure-activity relationships (SAR): How modifications to the chemical structure of antipsychotics affect their activity.
Synthesis of haloperidol: The chemical process used to create this medication.
Uses of antipsychotics: Treatment of psychosis, schizophrenia, delirium, and other mental health conditions.
Symptoms of psychosis: Hallucinations, delusions, abnormal behavior, and more.

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