This comprehensive document explores natural product-derived anticancer drugs, focusing on their classification, mechanisms of action, and clinical applications. Presented by a Master of Pharmacy (M.Pharm) student from Jamia Hamdard, New Delhi, it covers key topics such as:
Drug discovery from natural sources (plants, marine organisms, microbes)
Classification of anticancer drugs (alkaloids, taxanes, podophyllotoxins, etc.)
Mechanisms of action (microtubule stabilization, topoisomerase inhibition, apoptosis induction)
Case studies of Paclitaxel (Taxol), Docetaxel, Etoposide, and Teniposide
Structure-Activity Relationships (SAR) and side effects
Recent advances (nanoparticle delivery, QSAR modeling, novel plant-derived agents)
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